Triplatin tetranitrate
Triplatin tetranitrate is a novel trinuclear platinum complex. Triplatin tetranitrate blocks G2/M phase. Triplatin tetranitrate can covalently bind to the DNA bases. Triplatin tetranitrate exhibits significant antitumor effects against neuroblastoma[1][2].
Product Specifications
CAS Number
172903-00-3
UNSPSC
12352100
Target
DNA Alkylator/Crosslinker
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
N[Pt+2](NCCCCCCN[Pt+2](N)(N)[Cl-])(N)NCCCCCCN[Pt+2](N)(N)[Cl-].O=N([O-])=O.O=N([O-])=O.O=N([O-])=O.O=N([O-])=O
Molecular Formula
C12H40Cl2N14O12Pt3
Molecular Weight
1228.69
References & Citations
[1]Riccardi A, et al. In vitro and in vivo antitumor activity of the novel trinuclear platinum complex BBR 3464 in neuroblastoma. Cancer Chemother Pharmacol. 2001 Jun;47 (6) :498-504. |[2]Banerjee T, et al. Compacting effect of BBR3464, a new-generation trisplatinum anticancer agent, on DNA. Biochimie. 2010 Jul;92 (7) :846-51.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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