CL-283796
CL-283796 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. CL-283796 reduces low-density lipoprotein (LDL) cholesterol without affecting cholesterol absorption in African green monkeys. CL-283796 can be used for hypercholesterolemia research[1].
Product Specifications
CAS Number
107376-72-7
UNSPSC
12352005
Target
Acyltransferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
O=C(NC1=C(C)C=C(Cl)C=C1C)N(CCCCCCC)CC2=CC=C(CCC(C)C)C=C2
Molecular Formula
C28H41ClN2O
Molecular Weight
457.09
References & Citations
[1]Wrenn SM Jr, et al. ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys. J Lipid Res. 1995 Jun;36 (6) :1199-210.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
ACAT
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