CL-283796

CL-283796 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. CL-283796 reduces low-density lipoprotein (LDL) cholesterol without affecting cholesterol absorption in African green monkeys. CL-283796 can be used for hypercholesterolemia research[1].

Product Specifications

CAS Number

[107376-72-7]

UNSPSC

12352005

Target

Acyltransferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Cardiovascular Disease

Smiles

O=C(NC1=C(C)C=C(Cl)C=C1C)N(CCCCCCC)CC2=CC=C(CCC(C)C)C=C2

Molecular Formula

C28H41ClN2O

Molecular Weight

457.09

References & Citations

[1]Wrenn SM Jr, et al. ACAT inhibitors CL 283,546 and CL 283,796 reduce LDL cholesterol without affecting cholesterol absorption in African green monkeys. J Lipid Res. 1995 Jun;36 (6) :1199-210.