FK 584

FK 584 is a potent detrusor muscle contraction inhibitor. FK 584 possesses potent antimuscarinic activity and weak calcium channel blocking activity. FK 584 has demonstrated potent detrusor muscle inhibitory activity in various experimental models with a manageable risk of mydriasis. FK 584 can be used to study overactive bladder (OAB) .

Product Specifications

CAS Number

[138951-54-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Calcium Channel; mAChR

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Metabolic Disease; Neurological Disease

Smiles

CC(C)(C)N[C@H]1CC(C2=CC=CC=C2)(C3=CC=CC=C3)C=C1

Molecular Formula

C21H25N

Molecular Weight

291.43

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Taniguchi K, et al. Agents for the treatment of overactive detrusor. VIII. Synthesis and pharmacological properties of 4,4-diphenyl-2-cycloalkenylamines including FK584 and 3,3- or 4,4-diphenylcycloalkylamines. Chem Pharm Bull (Tokyo) . 1995 Jan;43 (1) :71-7.