Fonsartan

Fonsartan (HR720) is an AT1 receptor antagonist. Fonsartan can be used for the study of myocardial infarction (MI) [1][2].

Product Specifications

CAS Number

[153235-15-5]

Product Name Alternative

HR 720

UNSPSC

12352005

Target

Angiotensin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=C(SC)N=C(CCCC)N1CC2=CC=C(C3=C(S(=O)(N([K])C(NCCC)=O)=O)C=CC=C3)C=C2)O[K]

Molecular Formula

C26H30K2N4O5S2

Molecular Weight

620.87

References & Citations

[1]Xia QG, et al. Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure. Cardiovasc Res. 2001 Jan;49 (1) :110-7.|[2]Jin D, et al. Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo. Jpn J Pharmacol. 1997 Nov;75 (3) :259-66.