ZD-6169

ZD-2767 is a selective ATP-sensitive potassium channel agonist. ZD-276 reduces cell membrane excitability and contractility by activating KATP channels in bladder smooth muscle. ZD-2767 is promising for research of overactive bladder[1].

Product Specifications

CAS Number

[147696-46-6]

UNSPSC

12352005

Target

Potassium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Endocrinology

Smiles

O=C(NC1=CC=C(C(C2=CC=CC=C2)=O)C=C1)[C@](C)(O)C(F)(F)F

Molecular Formula

C17H14F3NO3

Molecular Weight

337.29

References & Citations

[1]Fryer RM, et al. (-) - (9S) -9- (3-Bromo-4-fluorophenyl) -2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8 (4H) -one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine. J Cardiovasc Pharmacol. 2004 Aug;44 (2) :137-47.