ZD-6169
ZD-2767 is a selective ATP-sensitive potassium channel agonist. ZD-276 reduces cell membrane excitability and contractility by activating KATP channels in bladder smooth muscle. ZD-2767 is promising for research of overactive bladder[1].
Product Specifications
CAS Number
147696-46-6
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Endocrinology
Smiles
O=C(NC1=CC=C(C(C2=CC=CC=C2)=O)C=C1)[C@](C)(O)C(F)(F)F
Molecular Formula
C17H14F3NO3
Molecular Weight
337.29
References & Citations
[1]Fryer RM, et al. (-) - (9S) -9- (3-Bromo-4-fluorophenyl) -2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8 (4H) -one 1,1-dioxide (A-278637), a novel ATP-sensitive potassium channel opener: hemodynamic comparison to ZD-6169, WAY-133537, and nifedipine in the anesthetized canine. J Cardiovasc Pharmacol. 2004 Aug;44 (2) :137-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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