CE-1037
CE-1037 (MDL 201,404YA) is a selective inhibitor of human neutrophil elastase (HNE) (Ki: 0.45 nM) . CE-1037 prevents the pulmonary hemorrhage induced by intratracheal instillation of HNE. CE-1037 can be used for research of pulmonary diseases, such as COPD[1].
Product Specifications
CAS Number
150493-09-7
Product Name Alternative
MDL 201,404YA
UNSPSC
12352005
Target
Elastase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=S(C1=CC=C(OC(C(C2=CC=C(C(C(OC3=CC=C(S(=O)(CC(C(O)=O)(C)C)=O)C=C3)=O)(C)C)C=C2)(C)C)=O)C=C1)(CC(C)(C)C(O)=O)=O
Molecular Formula
C36H42O12S2
Molecular Weight
730.84
References & Citations
[1]Ohbayashi H. Neutrophil elastase inhibitors as treatment for COPD. Expert Opin Investig Drugs. 2002 Jul;11 (7) :965-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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