Thiazolobenzimidazole

Thiazolobenzimidazole (NSC-625487) is a highly potent nonnucleoside HIV-1 reverse transcriptase inhibitor. Thiazolobenzimidazole inhibits HIV-induced cell killing and viral replication in a variety of human cell lines[1].

Product Specifications

CAS Number

[138226-12-7]

Product Name Alternative

NSC-625487

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

FC1=C(C2SCC3=NC4=CC=CC=C4N32)C(F)=CC=C1

Molecular Formula

C15H10F2N2S

Molecular Weight

288.32

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Buckheit RW Jr, et al. Thiazolobenzimidazole: biological and biochemical anti-retroviral activity of a new nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 1993 Jul;21 (3) :247-65.