Bay-X-7195
Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in vivo. Bay-X-7195 can be used foe the study of allergic and asthmatic[1][2].
Product Specifications
CAS Number
143538-27-6
UNSPSC
12352005
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C(O)C1=CC=C(S[C@@H](CCC(O)=O)/C=C\CC2=CC=C(OCCCCOC3=CC=CC=C3)C=C2)C=C1
Molecular Formula
C30H32O6S
Molecular Weight
520.64
References & Citations
[1]Boulet LP, et al. Inhibitory effects of BAY x 7195, a CYS leukotriene 1 receptor antagonist, on allergen-induced asthmatic responses. Ann Allergy Asthma Immunol. 1997 Aug;79 (2) :155-61. |[2]Tanaka H, et al. The effect of a novel leukotriene C4/D4 antagonist, BAY-x-7195, on experimental allergic reactions. Prostaglandins. 1995 Nov-Dec;50 (5-6) :269-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
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