CGS-22652
CGS 22652 is a potent thromboxane A2 receptor antagonist. CGS 22652 has selective thromboxane A2 synthase inhibitory properties. CGS 22652 can be used in the research of coronary artery thrombosis[1][2].
Product Specifications
CAS Number
134235-78-2
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
ClC1=CC=C(S(=O)(NCCCCC(CCCC2=CN=CC=C2)CCC(O)=O)=O)C=C1
Molecular Formula
C22H29ClN2O4S
Molecular Weight
452.99
References & Citations
[1]Cohen D S, et al. CGS 22652: A new potent thromboxane A2 receptor antagonist with selective thromboxane A2 synthase inhibitory properties. Cardiovascular drug reviews, 1992, 10 (4) : 379-391. |[2]Olson RW, et al. Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis. Eur J Pharmacol. 1993 May 12;236 (1) :75-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
TXA2/TP
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