CGS-22652

CGS 22652 is a potent thromboxane A2 receptor antagonist. CGS 22652 has selective thromboxane A2 synthase inhibitory properties. CGS 22652 can be used in the research of coronary artery thrombosis[1][2].

Product Specifications

CAS Number

[134235-78-2]

UNSPSC

12352005

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

ClC1=CC=C(S(=O)(NCCCCC(CCCC2=CN=CC=C2)CCC(O)=O)=O)C=C1

Molecular Formula

C22H29ClN2O4S

Molecular Weight

452.99

References & Citations

[1]Cohen D S, et al. CGS 22652: A new potent thromboxane A2 receptor antagonist with selective thromboxane A2 synthase inhibitory properties. Cardiovascular drug reviews, 1992, 10 (4) : 379-391. |[2]Olson RW, et al. Beneficial effects of combined thromboxane synthase inhibition/receptor blockade with CGS 22652 in a canine model of coronary thrombosis. Eur J Pharmacol. 1993 May 12;236 (1) :75-87.