FK-518

FK-518 is a potent AmpC β-lactamase inhibitor. FK-518 demonstrates strong antimicrobial activity against P. aeruginosa strains overexpressing AmpC β-lactamase. FK-518 is promising for research of P. aeruginosa infections[1].

Product Specifications

CAS Number

[1025510-45-5]

UNSPSC

12352005

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

OCC[N+](N1CC(CS[C@]2([H])[C@@H]3NC(/C(C4=NSC(N)=N4)=N\OC(C)(C(O)=O)C)=O)=C(C(O)=O)N2C3=O)=C(C=C1)N.[Cl-]

Molecular Formula

C21H26ClN9O8S2

Molecular Weight

632.07

References & Citations

[1]Murano K, et al. Structural requirements for the stability of novel cephalosporins to AmpC beta-lactamase based on 3D-structure. Bioorg Med Chem. 2008 Mar 1;16 (5) :2261-75.