FK 409
FK 409 is a NO donor that can penetrate cell membranes. FK 409 has a vasodilatory effect on bovine retinal arteries. FK 409 alleviates acute-phase inflammation, induces HSP, and mitigates liver transplantation injury in a rat model of orthotopic liver transplantation. FK 409 can be used in research on cardiovascular diseases and liver transplant rejection and inflammatory immune system disorders[1][2].
Product Specifications
CAS Number
[92454-60-9]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
HSP; NO Synthase
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
CC([N+]([O-])=O)/C(CC)=C/C(C(N)=O)=N/O
Molecular Formula
C8H13N3O4
Molecular Weight
215.21
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19090/
Scientific Category
Reference compound2
Clinical Information
Phase 2
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