BMS-180431
BMS-180431 is an inhibitor of HMG-CoA reductase (IC50: 43 nM) [1].
Product Specifications
CAS Number
[129829-03-4]
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(O)C[C@@H](O)C[C@@H](O)/C=C/C(C1=NN=NN1C)=C(C2=CC=C(F)C=C2)/C3=CC=C(F)C=C3
Molecular Formula
C23H22F2N4O4
Molecular Weight
456.44
References & Citations
[1]S.Y. Sit, et al. Synthesis of tetrazol-1-yl analogs of HMG-COA reductase inhibitor BMS180431 (formerly BMY21950) . Bioorganic & Medicinal Chemistry Letters. Volume 2, Issue 9, September 1992, Pages 1085-1088.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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