AGN-2979 (hydrochloride)
AGN-2979 (SC 48274) hydrochloride is a tryptophan hydroxylase activation inhibitor. AGN-2979 hydrochloride exhibits antidepressant and anxiolytic activities[1][2].
Product Specifications
CAS Number
103353-87-3
Product Name Alternative
SC 48274 (hydrochloride)
UNSPSC
12352005
Target
Tryptophan Hydroxylase
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(C(C1=CC=CC(OC)=C1)(CCCN(C)C)C(C)(C)C2)NC2=O.Cl
Molecular Formula
C19H29ClN2O3
Molecular Weight
368.90
References & Citations
[1]Gittos MW, et al. Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats. Eur Neuropsychopharmacol. 2001 Oct;11 (5) :351-7.|[2]Ogawa N, et al. Anxiolytic activity of SC-48274 compared with those of buspirone and diazepam in experimental anxiety models. Jpn J Pharmacol. 1993 Feb;61 (2) :115-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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