AGN-2979 (hydrochloride)

AGN-2979 (SC 48274) hydrochloride is a tryptophan hydroxylase activation inhibitor. AGN-2979 hydrochloride exhibits antidepressant and anxiolytic activities[1][2].

Product Specifications

CAS Number

[103353-87-3]

Product Name Alternative

SC 48274 (hydrochloride)

UNSPSC

12352005

Target

Tryptophan Hydroxylase

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(C(C1=CC=CC(OC)=C1)(CCCN(C)C)C(C)(C)C2)NC2=O.Cl

Molecular Formula

C19H29ClN2O3

Molecular Weight

368.90

References & Citations

[1]Gittos MW, et al. Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats. Eur Neuropsychopharmacol. 2001 Oct;11 (5) :351-7.|[2]Ogawa N, et al. Anxiolytic activity of SC-48274 compared with those of buspirone and diazepam in experimental anxiety models. Jpn J Pharmacol. 1993 Feb;61 (2) :115-21.