ACC-9358

ACC-9358 is an orally active sodium channel blocker. ACC-9358 has antiarrhythmic activity. ACC-9358 can be used in research on cardiovascular diseases such as arrhythmias[1][2].

Product Specifications

CAS Number

[90446-66-5]

UNSPSC

12352005

Target

Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Smiles

O=C(NC1=CC=CC=C1)C2=CC(CN3CCCC3)=C(O)C(CN4CCCC4)=C2

Molecular Formula

C23H29N3O2

Molecular Weight

379.50

References & Citations

[1]Pavlou HN, et al. Prospective pharmacokinetically based development of effective infusion regimens for ACC-9358, a new antiarrhythmic drug. Clin Pharmacol Ther. 1991 Mar;49 (3) :314-21.|[2]Brown BS, et al. Antiarrhythmic, electrophysiologic and hemodynamic effects of ACC-9358. J Pharmacol Exp Ther. 1987 Dec;243 (3) :1225-34.