Adjudin (Standard)

Adjudin (Standard) is the analytical standard of Adjudin. This product is intended for research and analytical applications. Adjudin is an extensively studied male contraceptive with a superior mitochondria-inhibitory effect. Adjudin is also a potent Cl- channel blocker.

Product Specifications

CAS Number

[252025-52-8]

UNSPSC

12352100

Target

Chloride Channel; Mitochondrial Metabolism; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Smiles

O=C(C1=NN(CC2=CC=C(Cl)C=C2Cl)C3=C1C=CC=C3)NN

Molecular Formula

C15H12Cl2N4O

Molecular Weight

335.19

References & Citations

[1]Li K, et al. Inhibition of sperm capacitation and fertilizing capacity by adjudin is mediated by chloride and its channels in humans. Hum Reprod. 2013 Jan;28 (1) :47-59.|[2]Li X, et al. Combination delivery of Adjudin and Doxorubicin via integrating drug conjugation and nanocarrier approaches for the treatment of drug-resistant cancer cells. J Mater Chem B. 2015 Feb 28;3 (8) :1556-1564.|[3]Xie QR, et al. Male contraceptive Adjudin is a potential anti-cancer drug. Biochem Pharmacol. 2013 Feb 1;85 (3) :345-55.