TAS-301 (Standard)

TAS-301 (Standard) is the analytical standard of TAS-301. This product is intended for research and analytical applications. TAS-301 is an inhibitor of smooth muscle cell migration and proliferation, and inhibits PKC activation induced by PDGF.

Product Specifications

CAS Number

[193620-69-8]

UNSPSC

12352100

Target

PKC; Reference Standards

Related Pathways

Epigenetics; Others; TGF-beta/Smad

Field of Research

Cardiovascular Disease

Smiles

O=C1NC2=C(C=CC=C2)/C1=C(C3=CC=C(OC)C=C3)/C4=CC=C(OC)C=C4

Molecular Formula

C23H19NO3

Molecular Weight

357.40

References & Citations

[1]Muranaka Y, et al. TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries. J Pharmacol Exp Ther. 1998 Jun;285 (3) :1280-6.|[2]Sasaki E, et al. TAS-301 blocks receptor-operated calcium influx and inhibits rat vascular smooth muscle cell proliferation induced by basic fibroblast growth factor and platelet-derived growth factor. Jpn J Pharmacol. 2000 Nov;84 (3) :252-8.