MG-101 (GMP)
MG-101 (GMP) (Calpain inhibitor I (GMP) ) is MG-101 produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1].
Product Specifications
CAS Number
110044-82-1
Product Name Alternative
Calpain inhibitor I (GMP) ; Ac-LLnL-CHO (GMP) ; ALLN (GMP)
UNSPSC
12352211
Target
Apoptosis; Proteasome
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(N[C@H](C=O)CCCC)[C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C
Molecular Formula
C20H37N3O4
Molecular Weight
383.53
References & Citations
[1]Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437 (2) :325-330.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported
Frequently Asked Questions
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