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FIT-039 (Standard)

FIT-039 (Standard) is the analytical standard of FIT-039. This product is intended for research and analytical applications. FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.

Product Specifications

CAS Number

1113044-49-7

UNSPSC

12352100

Target

CDK; CMV; DNA/RNA Synthesis; HSV; Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection

Smiles

FC1=CC(NC(C2=CC=NC=C2)=S)=C(N3CCCCC3)C=C1

Molecular Formula

C17H18FN3S

Molecular Weight

315.41

References & Citations

[1]Makoto Yamamoto, et al. CDK9 Inhibitor FIT-039 Prevents Replication of Multiple DNA Viruses. J Clin Invest. 2014 Aug;124 (8) :3479-88.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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