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DSA8

DSA8 is a type II kinase inhibitor with IRE1 RNase modulating activity. DSA8 can be used for the research of cancer, metabolic disease, suah as diabetes[1].

Product Specifications

CAS Number

1157857-37-8

UNSPSC

12352005

Target

IRE1

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer; Metabolic Disease

Smiles

CC1=CC=C(NC(C2=CC=C(CN3CCN(C)CC3)C=C2)=O)C=C1NC4=C(C5=NC=NC(NC6=CC=C(OC)C=C6)=N5)C=CC=N4

Molecular Formula

C35H37N9O2

Molecular Weight

615.73

References & Citations

[1]Wang L, et al. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec;8 (12) :982-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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