DSA8
DSA8 is a type II kinase inhibitor with IRE1 RNase modulating activity. DSA8 can be used for the research of cancer, metabolic disease, suah as diabetes[1].
Product Specifications
CAS Number
1157857-37-8
UNSPSC
12352005
Target
IRE1
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer; Metabolic Disease
Smiles
CC1=CC=C(NC(C2=CC=C(CN3CCN(C)CC3)C=C2)=O)C=C1NC4=C(C5=NC=NC(NC6=CC=C(OC)C=C6)=N5)C=CC=N4
Molecular Formula
C35H37N9O2
Molecular Weight
615.73
References & Citations
[1]Wang L, et al. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors. Nat Chem Biol. 2012 Dec;8 (12) :982-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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