BIRB-1017

BIRB-1017 is a potent inhibitor of p38 MAP kinase. BIRB-1017 can be used in inflammation research[1].

Product Specifications

CAS Number

[294848-51-4]

UNSPSC

12352100

Target

P38 MAPK

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

CC1=CC=C([N]2=C(NC(NC3=CC=C(C4=CC=C(CN5CCOCC5)N=C4)C6=C3C=CC=C6)=O)CC(C(C)(C)C)=N2)C=C1

Molecular Formula

C35H39N6O2

Molecular Weight

575.72

References & Citations

[1]Lu BZ, et al. Development of a Practical Synthesis of 4-[6- (Morpholinomethyl) -pyridin-3-yl] naphthalen-1-amine, a Key Intermediate for the Synthesis of BIRB 1017, a Potent p38 MAP Kinase Inhibitor. Synlett. 2013 Feb;24 (03) :317-22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

P38 MAPK

Curated Selection

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