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WB-BC-15

WB-BC-15 (WGB-BC-15) is a c-Abl kinase inhibitor. WB-BC-15 can increase radiation-induced germ-cell apoptosis, with an EC50 of 10.5 μM[1].

Product Specifications

CAS Number

[309760-28-9]

Product Name Alternative

WGB-BC-15

UNSPSC

12352005

Target

Bcr-Abl

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Purity

90.000000

Smiles

CC1=CC=C(NC(C2=CC=CN=C2)=O)C=C1NC3=NC=CC(C4=CC=CN=C4)=N3

Molecular Formula

C22H18N6O

Molecular Weight

382.42

References & Citations

[1]Deng X, et, al. Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation. Nat Genet. 2004 Aug;36 (8) :906-12.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18814/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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