WB-BC-15
WB-BC-15 (WGB-BC-15) is a c-Abl kinase inhibitor. WB-BC-15 can increase radiation-induced germ-cell apoptosis, with an EC50 of 10.5 μM[1].
Product Specifications
CAS Number
[309760-28-9]
Product Name Alternative
WGB-BC-15
UNSPSC
12352005
Target
Bcr-Abl
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Purity
90.000000
Smiles
CC1=CC=C(NC(C2=CC=CN=C2)=O)C=C1NC3=NC=CC(C4=CC=CN=C4)=N3
Molecular Formula
C22H18N6O
Molecular Weight
382.42
References & Citations
[1]Deng X, et, al. Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation. Nat Genet. 2004 Aug;36 (8) :906-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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