Carboxy-PTIO (potassium) (Standard)
Carboxy-PTIO (potassium) (Standard) is the analytical standard of Carboxy-PTIO (potassium) . This product is intended for research and analytical applications. Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model[1][2][3].
Product Specifications
CAS Number
148819-94-7
UNSPSC
12352100
Target
NO Synthase; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Smiles
[O]N1C(C)(C)C(C)(C)[N+]([O-])=C1C2=CC=C(C(O[K])=O)C=C2
Molecular Formula
C14H16KN2O4
Molecular Weight
315.39
References & Citations
[1]Hao He, et al.Nitric oxide induces apoptosis and autophagy; autophagy down-regulates NO synthesis in physalin A-treated A375-S2 human melanoma cells.Food Chem Toxicol. 2014 Sep;71:128-35.|[2]T Akaike, et al. Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.NO through a radical reaction. Biochemistry. 1993 Jan 26;32 (3) :827-32.|[3]M Yoshid, et al. Therapeutic effects of imidazolineoxyl N-oxide against endotoxin shock through its direct nitric oxide-scavenging activity. Biochem Biophys Res Commun. 1994 Jul 29;202 (2) :923-30.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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