L-NMMA (acetate) (Standard)
L-NMMA (acetate) (Standard) is the analytical standard of L-NMMA (acetate) . This product is intended for research and analytical applications. L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively.
Product Specifications
CAS Number
[53308-83-1]
UNSPSC
12352100
Target
Endogenous Metabolite; NO Synthase; Reference Standards
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease; Cancer
Smiles
N[C@@H](CCCNC(NC)=N)C(O)=O.O=C(C)O
Molecular Formula
C9H20N4O4
Molecular Weight
248.28
References & Citations
[1]Frey C, et al. L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269 (42) :26083-91.|[2]Maggi CA, et al. Effect of NG-monomethyl L-arginine (L-NMMA) and NG-nitro L-arginine (L-NOARG) on non-adrenergic non-cholinergic relaxation in the circular muscle of the human ileum. Br J Pharmacol. 1991 Aug;103 (4) :1970-2.|[3]Nakamura T, et al. Effect of NG-monomethyl-L-arginine on arcade arterioles of rat spinotrapezius muscles. Am J Physiol. 1991 Jul;261 (1 Pt 2) :H46-52.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18732AR/
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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