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Endoxifen (hydrochloride) (Standard)

Endoxifen (hydrochloride) (Standard) is the analytical standard of Endoxifen (hydrochloride) . This product is intended for research and analytical applications. Endoxifen hydrochloride is a key active metabolite of Tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen hydrochloride has the potential for breast cancer study[1][2].

Product Specifications

CAS Number

1197194-41-4

UNSPSC

12352005

Target

Cytochrome P450; Drug Metabolite; Estrogen Receptor/ERR; Parasite; Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)\CC)C=C1.[H]Cl

Molecular Formula

C25H28ClNO2

Molecular Weight

409.95

References & Citations

[1]Wu X, et al. The tamoxifen metabolite, Endoxifen, is a potent antiestrogen that targets estrogen receptor alpha fordegradation in breast cancer cells. Cancer Res. 2009 Mar 1;69 (5) :1722-7.|[2]Goetz MP, et al. Tamoxifen, endoxifen, and CYP2D6: the rules for evaluating a predictive factor. Oncology (Williston Park) . 2009 Dec;23 (14) :1233-4, 1236.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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