(R) -CYP3cide
(R) -CYP3cide ((R) -PF-4981517) is the R-isomer of CYP3cide. CYP3cide is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4).
Product Specifications
Product Name Alternative
(R) -PF-4981517
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
99.46
Smiles
CC1=CC=C(C2=C(C3=NN(C)C4=NC=NC(N5C[C@H](N6CCCCC6)CC5)=C43)C=NN2C)C=C1
Molecular Formula
C26H32N8
Molecular Weight
456.59
References & Citations
[1]Robert L Walsky, et al. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugs. Drug Metab Dispos. 2012 Sep;40 (9) :1686-97.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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