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BCMA CAR mRNA

BCMA CAR mRNA can express the CAR protein targeting human BCMA. BCMA CAR mRNA can trigger the transient expression of CAR, enabling T cells to be targeted without the need for permanent genetic modification. BCMA is a member of the tumor necrosis factor receptor superfamily 17 (TNFRSF17), also known as B-cell maturation antigen (CD269), which promotes B-cell survival and plays a role in regulating humoral immunity. BCMA is highly expressed in multiple myeloma and is a biomarker for the diagnosis of multiple myeloma.

Product Specifications

UNSPSC

12352208

Target

MRNA

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[BCMACARmRNA]

References & Citations

[1]Scheller L, Tebuka E, Rambau PF, et al. BCMA CAR-T cells in multiple myeloma-ready for take-off?. Leuk Lymphoma. 2024;65 (2) :143-157.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

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