BCMA CAR mRNA
BCMA CAR mRNA can express the CAR protein targeting human BCMA. BCMA CAR mRNA can trigger the transient expression of CAR, enabling T cells to be targeted without the need for permanent genetic modification. BCMA is a member of the tumor necrosis factor receptor superfamily 17 (TNFRSF17), also known as B-cell maturation antigen (CD269), which promotes B-cell survival and plays a role in regulating humoral immunity. BCMA is highly expressed in multiple myeloma and is a biomarker for the diagnosis of multiple myeloma.
Product Specifications
UNSPSC
12352208
Target
MRNA
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[BCMACARmRNA]
References & Citations
[1]Scheller L, Tebuka E, Rambau PF, et al. BCMA CAR-T cells in multiple myeloma-ready for take-off?. Leuk Lymphoma. 2024;65 (2) :143-157.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items