Walrycin B (Standard)

Walrycin B (Standard) is the analytical standard of Walrycin B. This product is intended for research and analytical applications. Walrycin B, an analogue of toxoflavin, is a potent SARS-CoV-2 3CLpro inhibitor with an IC50 of 0.26 μM. Walrycin B is a WalR response regulator inhibitor. Walrycin B has potent activity of inhibiting bacteria growth[1][2].

Product Specifications

CAS Number

[878419-78-4]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards; SARS-CoV

Related Pathways

Anti-infection; Others

Field of Research

Infection; Inflammation/Immunology

Smiles

O=C(C1=NC(C2=CC=C(C(F)(F)F)C=C2)=NN(C)C1=N3)N(C)C3=O

Molecular Formula

C14H10F3N5O2

Molecular Weight

337.26

References & Citations

[1]Gotoh Y, et al. Novel antibacterial compounds specifically targeting the essential WalR response regulator. J Antibiot (Tokyo) . 2010 Mar;63 (3) :127-34.|[2]Wei Zhu, et al. Identification of SARS-CoV-2 3CL Protease Inhibitors by a Quantitative High-throughput Screening. bioRxiv. 2020 Aug 11:2020.07.17.207019.