HBF-0079
HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma[1].
Product Specifications
CAS Number
[315702-93-3]
UNSPSC
12352005
Target
Akt; Apoptosis; mTOR
Related Pathways
Apoptosis; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1
Molecular Formula
C12H9N5S
Molecular Weight
255.30
References & Citations
[1]Cuconati A, et al. Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells. PLoS One. 2013;8 (1) :e54595.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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