HBF-0079

HBF-0079 is a selective anti-hepatocellular carcinoma agent. HBF-0079 induces cell cycle arrest and Apoptosis. HBF-0079 modulates cell-growth and anti-apoptotic signaling through AKT and mTOR. HBF-0079 exhibits antitumor activity against hepatocellular carcinoma[1].

Product Specifications

CAS Number

[315702-93-3]

UNSPSC

12352005

Target

Akt; Apoptosis; mTOR

Related Pathways

Apoptosis; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

C1(C2=CSC(NC3=NC=CC=N3)=N2)=NC=CC=C1

Molecular Formula

C12H9N5S

Molecular Weight

255.30

References & Citations

[1]Cuconati A, et al. Suppression of AKT anti-apoptotic signaling by a novel drug candidate results in growth arrest and apoptosis of hepatocellular carcinoma cells. PLoS One. 2013;8 (1) :e54595.