Cryptophycin 52
Cryptophycin 52 (LY355703) is a synthesized 16-membered cyclic ester peptide compound and is a derivative of marine natural product cryptophycin 1. Cryptophycin 52 shows inhibitory activity against various tumor cells with an IC50 of 24.8 pmol/L for HL-60 cells. Cryptophycin 52 can induce cells G2/M phase arrest. Cryptophycin 52 is also effective for solid tumors that are resistant to Paclitaxel and Doxorubicin (HY-15142A). Cryptophycin 52 can be used for the research of cancer, such as multidrug-resistant tumor[1].
Product Specifications
CAS Number
186256-67-7
Product Name Alternative
LY355703
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
C[C@@H]([C@@]1([H])OC([C@@H](OC(C(C)(CNC([C@H](NC(/C=C/C1)=O)CC2=CC(Cl)=C(C=C2)OC)=O)C)=O)CC(C)C)=O)[C@]3([H])[C@@H](C4=CC=CC=C4)O3
Molecular Formula
C36H45ClN2O8
Molecular Weight
669.20
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Escherichia coli O6 Protein sfa (sfa), partial
Chk2 (CHEK2) (NM_007194) Human Over-expression Lysate