Cryptophycin 52
Cryptophycin 52 (LY355703) is a synthesized 16-membered cyclic ester peptide compound and is a derivative of marine natural product cryptophycin 1. Cryptophycin 52 shows inhibitory activity against various tumor cells with an IC50 of 24.8 pmol/L for HL-60 cells. Cryptophycin 52 can induce cells G2/M phase arrest. Cryptophycin 52 is also effective for solid tumors that are resistant to Paclitaxel and Doxorubicin (HY-15142A). Cryptophycin 52 can be used for the research of cancer, such as multidrug-resistant tumor[1].
Product Specifications
CAS Number
186256-67-7
Product Name Alternative
LY355703
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
C[C@@H]([C@@]1([H])OC([C@@H](OC(C(C)(CNC([C@H](NC(/C=C/C1)=O)CC2=CC(Cl)=C(C=C2)OC)=O)C)=O)CC(C)C)=O)[C@]3([H])[C@@H](C4=CC=CC=C4)O3
Molecular Formula
C36H45ClN2O8
Molecular Weight
669.20
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound
Clinical Information
No Development Reported
Frequently Asked Questions
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