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SCPI-3

SCPI-3 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.159 µM; AeSCP-x IC50 = 0.285 µM) . SCPI-3 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 = 3.09 µM in Aag-2 cells) . SCPI-3 shows insecticidal activity against Aedes aegypti with a LD50 of 12.3 µM[1].

Product Specifications

CAS Number

[349561-46-2]

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

O=[N+]([O-])C1=CC2=C(C(OC)=C1)NC(C3=CC=C(Br)C=C3)=NO2

Molecular Formula

C14H10BrN3O4

Molecular Weight

364.15

References & Citations

[1]Kim MS, et al. Identification of mosquito sterol carrier protein-2 inhibitors. J Lipid Res. 2005 Apr;46 (4) :650-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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