5-HT2C antagonist 1
5-HT2C antagonist 1 (Compound 45) is a selective and orally active 5-HT2C receptor antagonist with a pKi of 8.0. 5-HT2C antagonist 1 can effectively antagonize the erection of the rat penis induced by mCPP. 5-HT2C antagonist 1 can be used for the researches of neurological disease and endocrinology, such as anxiety[1].
Product Specifications
CAS Number
204650-40-8
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology; Neurological Disease
Smiles
OC1=C2C([C@@]3([H])[C@](CCN(C3)C)([H])CC2=O)=CC(OC)=C1CC
Molecular Formula
C17H23NO3
Molecular Weight
289.37
References & Citations
[1]Bös M, et al. Syntheses of O‐Methylasparvenone‐Derived Serotonin‐Receptor Antagonists[J]. Helvetica chimica acta, 1998, 81 (3‐4) : 525-538.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
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