5-HT2C agonist-12
5-HT2C agonist-12 (example.2) is a selective and orally active 5-HT2C receptor agonist. 5-HT2C agonist-12 can inhibit the accumulation of IP3 with an IC50 of 4.5 nM. 5-HT2C agonist-12 can induce a feeling of fullness, shorten the time of eating, and reduce calorie intake. 5-HT2C agonist-12 can be used for the research of obesity[1].
Product Specifications
CAS Number
[616201-56-0]
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
ClC1=C(OC)C=C(CCNCC2C)C2=C1
Molecular Formula
C12H16ClNO
Molecular Weight
225.71
References & Citations
[1]Brian Smith, et al. 5ht2c receptor modulators. WO2003086306A2. 2004-10-12
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor
Curated Selection
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