SCPI-1
SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM) . SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 = 5.53 µM in Aag-2 cells) . SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM[1].
Product Specifications
CAS Number
[339231-67-3]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Others
Smiles
O=C(C)NC1=CC=C(NC2=NC(C3=CC(Cl)=C(Cl)C=C3)=CS2)C=C1
Molecular Formula
C17H13Cl2N3OS
Molecular Weight
378.28
References & Citations
[1]Kim MS, et al. Identification of mosquito sterol carrier protein-2 inhibitors. J Lipid Res. 2005 Apr;46 (4) :650-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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