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SCPI-1

SCPI-1 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.347 µM; AeSCP-x IC50 = 0.527 µM) . SCPI-1 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 = 5.53 µM in Aag-2 cells) . SCPI-1 shows insecticidal activity against Aedes aegypti with a LD50 of 4.8 µM[1].

Product Specifications

CAS Number

339231-67-3

UNSPSC

12352005

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

O=C(C)NC1=CC=C(NC2=NC(C3=CC(Cl)=C(Cl)C=C3)=CS2)C=C1

Molecular Formula

C17H13Cl2N3OS

Molecular Weight

378.28

References & Citations

[1]Kim MS, et al. Identification of mosquito sterol carrier protein-2 inhibitors. J Lipid Res. 2005 Apr;46 (4) :650-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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