GR 92549
GR 92549 is a potent, orally active, and competitive HMG-CoA reductase inhibitor, can be used as a cholesterol lowering agent[1].
Product Specifications
CAS Number
144501-27-9
UNSPSC
12352005
Target
HMG-CoA Reductase (HMGCR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
OC(C[C@@H](O)C[C@@H](O)/C=C/N1C(C2=CC=C(C=C2)F)=C(C3=CC=C(C=C3)F)N=C1C(C)C)=O
Molecular Formula
C25H26F2N2O4
Molecular Weight
456.48
References & Citations
[1]Beresford AP, et al. Advantages of achiral h.p.l.c. as a preparative step for chiral analysis in biological samples and its use in toxicokinetic studies. Xenobiotica. 1992 Jul;22 (7) :789-98.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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