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Glucagon receptor antagonist-11

Glucagon receptor antagonist-11 (Compound 14) is a glucagon receptor antagonist with a pIC50 of 6.677. Glucagon receptor antagonist-10 can be used in studies of glucose homeostasis[1].

Product Specifications

CAS Number

152121-19-2

UNSPSC

12352005

Target

GCGR

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Smiles

N#CC1=CC=C(C2=NC(C3=CC=NC=C3)=C(C4=CC=C(F)C=C4)N2)C=C1

Molecular Formula

C21H13FN4

Molecular Weight

340.35

References & Citations

[1]Shahlaei M, et al. Prediction of glucagon receptor antagonist activities of some substituted imidazoles using combined radial basis function neural network and density functional theory. Medicinal Chemistry Research, 2014, 23 (6) : 2744-2756.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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