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Glucagon receptor antagonist-9

Glucagon receptor antagonist-9 (compound 13) is a potent glucagon receptor antagonist with a pIC50 of 7.000[1].

Product Specifications

CAS Number

[152121-61-4]

UNSPSC

12352005

Target

GCGR

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

FC1=CC=C(C2=C(C3=CC=NC=C3)N=C(C4=CC=C(OC)C=C4)N2)C=C1

Molecular Formula

C21H16FN3O

Molecular Weight

345.37

References & Citations

[1]Shahlaei M, et al. Prediction of Glucagon Receptor Antagonist Activities of Some Substituted Imidazoles Using Combined Radial Basis Function Neural Network and Density Functional Theory. Medicinal Chemistry Research 2013, 23 (6), 2744-2756.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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