CU-6PMN
CU-6PMN is a fluorescent RXR agonist. CU-6PMN has a maximum absorption wavelength of 396 nm and an emission wavelength of 453 nm in 0.1 N NaOH aqueous solution. CU-6PMN has an EC50 value of 22 nM and a Ki value of 230 nM for human RXRα. CU-6PMN can be used in research related to the screening of RXR ligands[1].
Product Specifications
CAS Number
2099034-38-3
UNSPSC
12352005
Target
RAR/RXR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Others
Smiles
O=C(O)C1=CC2=CC(=C(O)C=C2OC1=O)C3=CC4=C(C=C3C)C(C)(C)CCC4(C)C
Molecular Formula
C25H26O5
Molecular Weight
406.48
References & Citations
[1]Yamada S, et al. Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening. J Med Chem. 2019 Oct 10;62 (19) :8809-8818.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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