UR-12633
UR-12633 is a platelet-activating factor (PAF) antagonist. UR-12633 can effectively reverse hypotension, inhibit coagulation abnormalities, increased vascular permeability, and metabolic disorders in rodent models of endotoxic shock. UR-12633 can be used for research on endotoxic shock[1].
Product Specifications
CAS Number
[179912-83-5]
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
N#CC(C=1C=NC=CC1)C2CCN(C(=O)CC(C=3C=CC=CC3)C=4C=CC=CC4)CC2
Molecular Formula
C27H27N3O
Molecular Weight
409.53
References & Citations
[1]Giral M, et al. Effects of UR-12633, a new antagonist of platelet-activating factor, in rodent models of endotoxic shock. Br J Pharmacol. 1996 Jul;118 (5) :1223-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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