NAT6-297775
NAT6-297775 (Compound 29) is a protein tyrosine phosphatase (PTP) inhibitor targeting non-receptor PTP SHP-2 with an IC50 of 2.5 μM. NAT6-297775 can inhibit the RAS/MAP kinase signaling pathway. NAT6-297775 can be used for the research of cancer, such as leukemia[1].
Product Specifications
CAS Number
1348433-02-2
UNSPSC
12352005
Target
Phosphatase; SHP2
Related Pathways
Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
N(CC1CCCCC1)[C@H]2O[C@@]3([C@H](CO[C@@]3(C2)[H])N4C(=NN=N4)C5=CC(CN6CCCC6)=CC=C5)[H]
Molecular Formula
C25H36N6O2
Molecular Weight
452.60
References & Citations
[1]Vintonyak VV, et al. Using small molecules to target protein phosphatases. Bioorg Med Chem. 2011 Apr 1;19 (7) :2145-55.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
176944 750 Roll (750 Label (s) x 1 Roll)
M7-25-768 Pre-sized Labels for Printers
Sign In for Pricing
View Details 
MBS8434559-01 0.002 mg
Rat Oncostatin M Recombinant Protein Lyophilized
Sign In for Pricing
View Details