MI-30
MI-30 is an orally active SARS-CoV-2 3CLpro inhibitor (IC50 = 17.2 nM) . MI-30 reduces viral load and lung lesions in a mouse model of SARS-CoV-2 infection. MI-30 may be used in coronavirus infection research[1].
Product Specifications
CAS Number
[2698348-97-7]
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@@H]2[C@]3([H])[C@](CCC3)([H])CN2C(COC4=C(C=C(C=C4)Cl)Cl)=O)=O
Molecular Formula
C23H27Cl2N3O5
Molecular Weight
496.38
References & Citations
[1]Qiao J, et al. SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model. Science. 2021 Mar 26;371 (6536) :1374-1378.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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