Antibacterial agent 309
Antibacterial agent 309 (Compound C9) is an antibacterial agent, substrate of AcrB efflux pump. Antibacterial agent 309 promotes FtsZ polymerization. Antibacterial agent 309 demonstrates antibacterial activity against Erythromycin -resistant S. pyogenes 2 (MIC = 0.25 μg/mL), Penicillin-resistant S. aureus CI (MIC = 0.125 μg/mL), Penicillin-resistant S. epidermidis (MIC = 2 μg/mL). Antibacterial agent 309 exhibits weak antibacterial activity against the wild-type E. coli BW25113 MIC = 256 μg/mL).
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
C[N+]1=C(/C=C/C2=CC=C(F)C=C2)N=C(/C=C3SC(C=CC=C4)=C4N\3C)C5=CC=CC=C51.[I-]
Molecular Formula
C26H21FIN3S
Molecular Weight
553.43
References & Citations
[1]Zhang S, et al. Novel 1-Methylquinazoline and 1-Methylquinoxaline derivatives targeting FtsZ protein: Potent antibacterial agents against gram-positive bacteria. Bioorg Chem. 2025 Dec;167:109282.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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