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SGLT2-IN-4

SGLT2-IN-4 (Compound 1) is a selective and orally active sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor. SGLT2-IN-4 can increase the proportion of protein α-helix and enhance the stability of the SGLT2-D201A mutant. SGLT2-IN-4 can be used for the research of type 2 diabetes[1].

Product Specifications

UNSPSC

12352005

Target

SGLT

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Metabolic Disease

Smiles

[H][C@@]1(O[C@H]([C@@H]([C@H]([C@@H]1O)O)O)CO)C2=C(C=C(C(CC3=CC=C(C=C3)OCC)=C2)Cl)CCOCCO

Molecular Formula

C25H33ClO8

Molecular Weight

496.98

References & Citations

[1]Haque A, et al. Identification of New Small-Molecule SGLT2 Inhibitors: In-Silico Approach to Therapeutics for Diabetes-Related Complications[J]. ACS Omega, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SGLT2

Curated Selection

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