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MEK-IN-9

MEK-IN-9 (Compound 4-82) is a MEK inhibitor. MEK-IN-9 induces p15 and p27 protein. MEK-IN-9 can be used in the research of renal adenocarcinoma and colorectal cancer[1].

Product Specifications

CAS Number

[871701-39-2]

UNSPSC

12352005

Target

CDK; MEK

Related Pathways

Cell Cycle/DNA Damage; MAPK/ERK Pathway

Field of Research

Cancer

Smiles

O=C1C2=C(N(C)C(C(C)=C2N(C3=CC(NC(CO)=O)=CC=C3)C(N1C4CC4)=O)=O)NC5=CC=C(C=C5F)I

Molecular Formula

C26H23FIN5O5

Molecular Weight

631.39

References & Citations

[1]Toshiyuki Sakai, et al. 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2h-pyrido’2,3-d! pyrimidine derivatives and related compounds for the treatment of cancer. WO2005121142A1. WIPO (PCT) . 2005-06-10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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